Efek Kontak TB Terhadap Kasus Tuberkulosis Pada Wilayah Prevalensi Tinggi: Meta Analisis

Abstract

Tuberculosis (TB) is a direct infectious disease caused by the bacterium Mycobacterium tuberculosis. TB bacteria mostly attack the lungs, but can also affect other organs (National Guidelines for Tuberculosis Management Medical Services, 2020). Indonesia will rank second after India in having a high TB burden. It is recorded that 969 thousand people suffer from TB in Indonesia, equivalent to one person every 33 seconds, with a TB death rate of 144 thousand people (WHO, 2024). This study aims to examine the risk factors including TB contact to tuberculosis in high prevalence areas using meta-analysis. The meta-analysis study was conducted using the PRISMA flow diagram and the PICO model. Population: ages 15 to 65 years. Intervention: having a history of TB contact. Comparison: not having a history of TB contact. Outcome: tuberculosis. The databases used are PubMed, Proquest, and Google Scholar with the keywords “(Tuberculosis OR TBC OR TB) AND Cross Sectional AND "Risk Factors" AND aOR.” Primary studies are focused on cross-sectional studies published between 2020 and 2025 that meet the inclusion criteria. Data processing and analysis performed using RevMan 5.3.